Tube Sealers, Filter Integrity Testers & Cell Disruptors
TUBE SEALERS
LePurseal Automatic Aseptic Sealer – Secure & Reliable Tube Sealing
Tube sealing is essential for maintaining aseptic conditions in bioprocessing, ensuring sterility and containment in fluid transfer systems. LePurseal’s Automatic Aseptic Sealer II provides a flexible and efficient heat-sealing solution, allowing for the disconnection of thermoplastic tubes while preserving closed-system integrity in non-sterile environments.
Lepure Biotech – Innovation in Aseptic Sealing
Lepure Biotech specializes in advanced single-use technologies, offering high-performance aseptic sealing solutions for the biopharmaceutical industry. The LePurseal Automatic Aseptic Sealer II enhances process safety and compliance, supporting sterile fluid management in critical applications such as monoclonal antibodies, vaccines, and cell & gene therapy production.
LePurseal Automatic Aseptic Sealer II – Flexible & Secure Sealing
The LePurseal Automatic Aseptic Sealer II is a versatile and user-friendly sealing system designed for TPE and thermoplastic pump tubes. Its optimized operation system improves efficiency, traceability, and compliance, making it an ideal solution for sterile disconnection in biomanufacturing.
Key Features:
- Compatible with tube diameters from 1/4” to 1”, sealing dry, wet, or liquid-filled tubing
- Pre-configured settings for commonly used tubing brands, ready for immediate use
- Built-in 32GB memory for secure data storage and audit tracking
- One-click login and unique account identification for enhanced traceability
- Pre-positioning function to minimize incorrect tubing placement
- Lightweight and portable for easy integration across different production areas
Applications:
- Aseptic disconnection in monoclonal antibody production
- Vaccine manufacturing and sterile fluid management
- Cell and gene therapy bioprocesses
- Integration into single-use bioprocessing workflows
How Vigenius Biotech Supports Your Bioprocess Needs
As the official distributor of Lepure Biotech in the LATAM region, Vigenius Biotech provides expert guidance, technical support, and after-sales service for LePurseal aseptic sealing solutions.
- Assistance in system selection and process integration
- Regulatory compliance support for aseptic fluid handling
- Technical support and troubleshooting
- Maintenance services and spare parts availability
📩 Want to learn more? Contact us at [email protected]
FILTER INTEGRITY TESTERS
Lesiever – High-Precision Filter Integrity Testing by Lepure Biotech
Ensuring filtration integrity is critical in biopharmaceutical manufacturing, guaranteeing sterility, regulatory compliance, and process reliability. Advanced integrity testing solutions, such as the GS-842, provide automated, accurate, and reproducible testing for sterilizing filters, virus removal filters, and ultrafiltration membranes.
Lepure Biotech – Innovation in Filtration Integrity Testing
Lepure Biotech specializes in cutting-edge filtration solutions, developing advanced integrity testers to meet the highest industry standards. The GS-842 Filter Integrity Tester is the latest generation of a fully automated, high-precision testing platform, designed to enhance efficiency, data security, and compliance with GMP and ALCOA principles.
GS-842 Filter Integrity Tester – Automated & Reliable Performance
The GS-842 Filter Integrity Tester is a full-featured testing system designed for liquid and gas filtration integrity verification. Equipped with real-time data analysis, automatic airflow regulation, and secure audit tracking, it offers fast and precise testing while ensuring compliance with industry regulations.
Key Features:
- Comprehensive testing methods, including bubble point, diffusion flow, pressure decay, and water intrusion
- Real-time data display and analysis, improving filtration performance monitoring
- Advanced algorithms reducing testing time by 20-30% while maintaining accuracy
- Secure data management with USB, SD card, and Ethernet connectivity
- Four-level authorization management ensuring database security and GMP compliance
- Permanent test result storage, allowing for traceable and verifiable audit trails
Applications:
- Integrity testing of liquid and gas sterilizing filters
- Verification of ultrafiltration membrane packs and hollow fiber membrane columns
- Integrity testing of virus removal filters
- Pressure integrity testing of stainless steel filtration systems
How Vigenius Biotech Supports Your Filtration Needs
As the official distributor of Lepure Biotech in the LATAM region, Vigenius Biotech provides expert guidance, implementation support, and after-sales service for the GS-842 Filter Integrity Tester.
- Selection and customization of filtration integrity testing systems
- Regulatory compliance and GMP validation support
- Technical assistance and troubleshooting
- Maintenance services and spare parts availability
📩 Want to learn more? Contact us at [email protected]
CELL DISRUPTORS
Continuous Flow Cell Disruptors – Precision & Scalability in Cell Lysis
Cell disruption is a critical step in bioprocessing, ensuring efficient extraction of intracellular components for research and industrial applications. Constant Systems’ CF series of Continuous Flow Cell Disruptors provide high-pressure, precise, and reproducible lysis, making them ideal for bacteria, yeast, algae, and other sample types.
Constant Systems’ HFR, CF1, and CF2 cell disruptors deliver high-pressure homogenization for efficient and reproducible cell lysis. These systems maximize protein recovery while maintaining product integrity, making them ideal for recombinant protein production, microbial fermentation, and vaccine development. Designed for scalability and precision, Constant Systems’ disruptors offer automated pressure control, minimal heat generation, and consistent performance, ensuring superior downstream processing for biopharmaceutical applications.
Constant Systems – Advanced Cell Disruption Technology
Constant Systems specializes in high-performance cell disruption solutions, offering scalable and fully controlled hydraulic systems that ensure consistent processing across all volumes. The CF1 and CF2 models provide continuous-flow processing with precise pressure control, eliminating the need for multiple passes and improving sample integrity and reproducibility.
CF1 Model – Compact & Versatile for Small-Scale Processing
The CF1 Cell Disruptor is a bench-mountable or trolley-mounted unit, ideal for processing volumes between 15mL and 10L. With a maximum pressure of 40 kpsi (2700 bar), it ensures high-efficiency lysis in a single pass, eliminating the need for multiple processing cycles. The CF1 can be equipped with an integrated peristaltic pump, maintaining continuous sample flow and preventing sedimentation during processing.
Key Features:
- Compact footprint (700mm²), adaptable for bench or trolley mounting
- Processing speed up to 6L per hour, making it ideal for small-to-medium-scale applications
- Integrated peristaltic pump (optional) for continuous feeding and recirculation
- Compatible with fluid, re-suspended, viscous, and frozen samples
- Digitally controlled pressure adjustment, ensuring repeatable and precise results
Applications:
- Bacterial, yeast, and algae cell lysis
- Protein extraction for biopharmaceutical research and production
- Sample preparation for biotechnology and life sciences
CF2 Model – Scalable Solution for High-Volume Processing
The CF2 Cell Disruptor is a floor-standing unit, designed for larger-scale cell disruption, handling volumes from 15mL to 100L. It features an integrated peristaltic pump as standard, ensuring a continuous and uniform flow of samples. The high-pressure hydraulic control guarantees that 99% of the sample is processed at the set pressure, ensuring reproducibility and efficiency.
Key Features:
- Floor-standing model with a stable, compact footprint (700mm²)
- Processing speed up to 24L per hour, ideal for large-scale bioprocessing
- Integrated peristaltic pump for continuous flow and sample homogeneity
- No need for compressed air or gas, operates on standard electrical supply
- Industry-standard cleaning compatibility, allowing easy cleaning and sterilization
Applications:
- Large-scale bacterial and yeast cell lysis
- Protein and nucleic acid extraction for industrial biomanufacturing
- High-throughput biotechnology and pharmaceutical applications
How Vigenius Biotech Supports Your Cell Disruption Needs
As the official distributor of Constant Systems in the LATAM region, Vigenius Biotech provides expert consultation, implementation support, and after-sales service for CF series cell disruptors.
- Assistance in selecting the right model based on process scale and application
- Regulatory compliance support for biopharmaceutical production
- Technical support and troubleshooting
- Maintenance services and spare parts availability
CONTACT US
Need cutting-edge equipment, tailored solutions, or expert consulting? Our team is ready to help. Schedule a consultation today!
Vigenius Biotech is committed to providing top-tier bioprocessing solutions tailored to the needs of biotech companies in the region. Our team offers expert consulting, cutting-edge equipment, and personalized support to help your organization achieve scalability and efficiency in biomanufacturing.
📩 Get in Touch:
- Email: [email protected]
- Phone: +1 (754) 248-7907
Let’s work together to drive innovation and optimize your bioprocesses!