DOWNSTREAM

Chromatographs, Resins & Columns

Advanced purification technologies to ensure high-yield protein recovery and compliance with regulatory standards.

CROMATOGRAPHS

High-Performance Chromatographs by Lisure

Reliable and precise chromatography systems for efficient biomolecule separation

APPS Process Chromatography System – Scalable & Automated Separation

Process chromatography is essential for large-scale purification of biological products, ensuring high efficiency and regulatory compliance. Automated chromatography systems streamline equilibration, sample injection, washing, elution, and regeneration, reducing manual intervention and enhancing process consistency.

Lisure – Advanced Solutions for Process Chromatography

Lisure specializes in innovative chromatography technologies for biopharmaceutical manufacturing. Their APPS Process chromatography system is designed for hygienic, automated, and scalable separation, ensuring compliance with ASME BPE and cGMP standards. With a modular and customizable design, it adapts to various production-scale purification processes.

Low Pressure Process-scale Automated Chrom System
Lisure partner Vigenius Biotech

APPS Process Chromatography System – Automated & Scalable Purification

Key Features:

  • Multiple control platforms available, including Emerson DeltaV, Siemens WinCC, and CBS software, all compliant with FDA 21 CFR Part 11
  • Hygienic design following ASME BPE and cGMP requirements
  • User-friendly interface for simple and stable operation
  • Customizable configurations to meet specific process needs
  • Flow rate range from 3 L/H to 16,000 L/H, covering diverse production scales
  • High accuracy with a 1% flow rate precision
  • Integrated UV, pH, and conductivity detection for precise process monitoring

Applications:

  • Purification of monoclonal antibodies, recombinant proteins, and vaccines
  • Separation of biopharmaceutical intermediates
  • Downstream processing in commercial-scale biomanufacturing

How Vigenius Biotech Supports Your Chromatography Needs

As the official distributor of Lisure in the LATAM region, Vigenius Biotech provides expert guidance, implementation support, and after-sales service for APPS Process chromatography systems.

  • Assistance in system selection and customization
  • Regulatory compliance support for cGMP and ASME BPE
  • Technical support and process optimization
  • Maintenance services and spare parts availability

📩 Want to learn more? Contact us at [email protected]

RESINS

Tosoh Resins – Optimized Purification for Biopharmaceuticals

High-performance chromatography resins for superior protein purification and recovery

Tosoh’s TOYOPEARL® and TSKgel® resins are industry-leading solutions for high-yield protein purification in bioprocessing. Engineered for high binding capacity, robust stability, and scalability, Tosoh resins enhance downstream purification processes, ensuring optimal performance in affinity, ion exchange, and hydrophobic interaction chromatography. These resins are trusted by biomanufacturers for monoclonal antibody purification, recombinant protein production, and plasma fractionation.

tosoh super A resins
toyopearl-af-rprotein-l-650f-45-m-1000-a-1l

TOYOPEARL Super A – High-Capacity Affinity Resin for mAbs Purification

TOYOPEARL Super A is a next-generation Protein A affinity resin designed for the high-efficiency purification of monoclonal antibodies (mAbs). It offers superior binding capacity, enhanced alkaline stability, and an optimized elution profile, ensuring maximum mAb recovery with minimal elution volume.

Key Features:

  • High dynamic binding capacity for efficient antibody purification
  • Superior alkaline stability for extended resin lifetime
  • Optimized elution conditions for minimal ligand leakage
  • Ideal for high-titer mAb production with improved ligand durability
  • Enhances process economy by reducing ligand degradation and maximizing resin lifespan

Applications:

  • Purification of monoclonal antibodies (mAbs)
  • Biopharmaceutical manufacturing of high-yield therapeutic proteins
  • Scalable for clinical and commercial production

How Vigenius Biotech Supports Your Chromatography Needs

As the official distributor of Tosoh in the LATAM region, Vigenius Biotech offers expert consultation, technical support, and after-sales service for TOYOPEARL resins. Our team ensures:

  • Guidance on selecting the optimal resin for your purification process
  • Technical support for process optimization and scalability
  • Regulatory compliance assistance for cGMP manufacturing
  • Availability of Tosoh resins for large-scale production

📩 Want to learn more? Contact us at [email protected]

COLUMNS

Axial Compression Chromatography Columns – Precision & Scalability

Robust and scalable chromatography columns for high-purity bioprocessing

Chromatography columns are essential for high-efficiency biomolecule separation, ensuring reproducible and consistent purification processes in biopharmaceutical manufacturing. Lisure’s axial compression columns are designed for cGMP production, offering hygienic, user-friendly, and scalable solutions for downstream processing.

Lisure – Advanced Chromatography Column Technology

Robust and scalable chromatography columns for high-purity bioprocessing

Lisure specializes in high-performance chromatography systems, providing customizable and automated solutions for purification processes. Their electrical motor-driven axial compression columns offer enhanced flow distribution, easy maintenance, and compliance with FDA/USP Class VI standards, ensuring efficiency and reliability in large-scale biomanufacturing.

Electrical Motor Driven Axial Compression Columns
Lisure partner Vigenius Biotech
Axial Compression Columns – Optimized for Bioprocessing

Lisure’s axial compression columns are engineered for high-precision packing, reproducible results, and seamless operation. Their patented distribution plate design ensures even flow distribution, enhancing separation efficiency and product recovery.

Key Features:

  • Hygienic CIP-compatible design, meeting FDA/USP Class VI standards
  • Patented distributor plate ensuring uniform flow distribution
  • Transparent acrylic column tube with a rotatable design for easy cleaning and maintenance
  • Motorized axial compression system for precise and reproducible packing
  • Customizable configurations to fit various process requirements
  • IQ/OQ documentation support for validation and regulatory compliance

Applications:

  • Purification of monoclonal antibodies, recombinant proteins, and viral vectors
  • Large-scale downstream processing in commercial biomanufacturing
  • Process development and optimization for high-purity biomolecule separation
How Vigenius Biotech Supports Your Bioprocess Needs

As the official distributor of Lisure in the LATAM region, Vigenius Biotech provides expert guidance, implementation support, and after-sales service for axial compression chromatography columns.

  • Assistance in system selection and customization
  • Regulatory compliance support for cGMP production
  • Technical support and troubleshooting
  • Maintenance services and spare parts availability
CONTACT US

Need cutting-edge equipment, tailored solutions, or expert consulting? Our team is ready to help. Schedule a consultation today!

Vigenius Biotech is committed to providing top-tier bioprocessing solutions tailored to the needs of biotech companies in the region. Our team offers expert consulting, cutting-edge equipment, and personalized support to help your organization achieve scalability and efficiency in biomanufacturing.

📩 Get in Touch:

Let’s work together to drive innovation and optimize your bioprocesses!

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